Tafnext

Tafnext 25mg

Composition : Tenofovir Alfenamide- 25mg 

Classification: Hepatitis B Medicine 

What is Tafnext?

It is an antiviral medicine that controls chronic Hepatitis B and HIV-1 infections.

Uses of Tafnext 

• Chronic Hepatitis B 

• As a combination therapy in HIV-1 infections 

How does it work?

It inhibits the enzyme that causes viral replication and multiplication.

It causes natural viral cell death.

Benefits  

• Targeted action, fewer side effects 

• Significant viral suppression 

• Lesser effect on kidney functions

• Improved liver functions 

• Better bone mineral density 

• Well tolerated 

Common side effects 

Nausea, dizziness, headache, digestive issues, tiredness, diarrhea, and abdominal pain.

Serious side effects 

• Lactic Acidosis – unusual pain, breathing issues, irregular heartbeats, abdominal pain.

• Irregular heartbeat – Arrhythmia

• Deep or rapid breathing 

• Enlarged fatty liver 

• Severely low phosphate levels cause muscle weakness 

• Pale hands and feet (blue coloration)

• Dark urine, yellow eyes, pale stool 

• Fluid retention-swelling of joints 

• Sudden inflammatory reaction on starting the treatment.

Precautions 

To be used cautiously in patients with: 

• Kidney disorders 

• HIV—Co-infections 

• Liver transplant 

• Elderly Patients 

• Postmenopausal women

• People at risk of osteoporosis 

Contraindication—

• Not to be used if any previous allergy or hypersensitivity to tenovofir or any excipients.

• Breastfeeding mothers 

• Pregnant women 

• It should not be used as monotherapy for HIV patients 

Warning 

To be used under medical prescription only 

Important Safety and Monitoring Information 

• Regular monitoring of the liver function, renal function, and bone density.

• Screen for viral load and HIV infections before treatment initiation.

• Hepatitis B flares, if the medicine is abruptly discontinued.

Treatment Instructions 

• It must be taken consistently to get effective viral suppression.

• Missing doses increase the risk of relapse and drug resistance.