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Ledikast
Hepatitis CBrand: Aprazer HealthcarePrescription Required

Ledikast

Molecular Salt: Sofosbuvir / Ledipasvir

Classification - Hepatitis C Medicine

Sofosbuvir + Ledipasvir combination -

Trusted combination of antiviral drugs effective against Hepatitis C genotypes 1,4,5,6.

Can be used in cirrhosis (both compensated and decompensated).

Can be used in HIV co-infections.

In children> 3 years

Can be used post-liver transplant

Uses -

Chronic Hepatitis C

HCV-HIV co-infections

Working of Sofosbuvir and ledipasvir

It inhibits viral cell replication by inhibiting two different protein polymerases, offering potent viral suppression.

Benefits

Short-term treatment

High cure rates

Low resistance risk

Well tolerated

Reduces liver damage

Common Side Effects

Nausea, dizziness, headache, digestive issues, tiredness, muscle pain, joint pain

Serious Side Effects

Severe Bradycardia (when taken with amiodarone)

Causes Hepatitis B reactivation.

Severe liver failure.

Severe anemia upon use with ribavirin.

Depression, mood swings, and confusion

Precautions

To be used cautiously in patients

Kidney disorders

cardiac disorders

Liver disorder

Hepatitis B co-infections- cause reactivation

HIV co-infection

When used in combination with ribavirin and amiodarone

Contraindications

Allergy or hypersensitivity to drug components.

Breastfeeding mothers

Pregnant women

Should not be used with Amiodarone, Antacids, and proton pump inhibitors.

Warning

To be taken under the instructions of the doctor.

Important Safety and Monitoring Information

Regular monitoring of hepatic functions,

Renal functions,

Cardiac functions,

Co-infections, and

Neuropsychiatric adverse reactions.

Drug interactions - Ribavirin and Amiodarone

Not to be used alone for HCV infections.

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Manufacturer

Aprazer Healthcare

Dosage / Formulation

Tablet (400MG/90MG)

Packaging Size

28 Tablets

Storage Protocol

Store below 30°C

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Storage Warning: Biological injectables, biosimilars, and active oncology agents are flagged as temperature-sensitive cargo and are packed strictly inside thermal containers coupled with real-time digital temperature tags.

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